The Drosophila Trio Plays an Essential Role in Patterning of Axons by Regulating Their Directional Extension
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منابع مشابه
The Drosophila Trio Plays an Essential Role in Patterning of Axons by Regulating Their Directional Extension
We identified the Drosophila trio gene, which encodes a Dbl family protein carrying two Dbl homology (DH) domains, each of which potentially activates Rho family GTPases. Trio was distributed along axons in the central nervous system (CNS) of embryos and was strongly expressed in subsets of brain regions, including the mushroom body (MB). Loss-of-function trio mutations resulted in the misdirec...
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ژورنال
عنوان ژورنال: Neuron
سال: 2000
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)81143-5